Description
Klinik der Kinderkrankheiten Breitscheidstr. 10 This increase reflects a realization This increase reflects a realization that the biology of bacteria in natural conditions is generally not that of logarithmic growth and that we have very limited information on the physiology of the energy and nutrient limited phases of the life cyde of the bacterial cello The growing interest in nongrowing bacteria also sterns from the more recent advances on the molecular basis of the starvation induced nongrowing bacterial cello The identification of starvation specific gene and protein re sponders in Escherichia coli as weIl as other bacterial species has provided molecular handles for our attempts to decipher the "differentiation like" responses and programs that nondifferentiating bacteria exhibit on nutrient limited growth arrest " can lead to a greater understanding than a sim ple response to "Is this right